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Recently, Louisville has surfaced as a major center for the health care and healthcare sciences industrial sectors. Louisville has been central to advancements in heart and hand surgery treatment as well as cancer healing. Several of the very first artificial cardiovascular system transplants were practiced in Louisville. Louisville's blooming downtown medical research grounds includes the unique $88 thousand rehab gathering place, and a wellness sciences exploration and commercialization recreation area that, in alliance with the University of Louisville, has lured nearly 80 main people and investigators. Louisville is actually also home to Humana, just one of the nation's most significant health insurance plan companies.

Louisville is residence to several major companies and organizations.